At NanoTech, we have developed versatile liposome-based technology platforms that can be used for the encapsulation and delivery of drug compounds with different physicochemical properties.
Our technology greatly enlarges the range of functional therapeutic compounds amenable to encapsulation in liposomes.
Low toxicity and immunogenicity
Exhibit sustained drug release profile to achieve long-acting therapeutic effects
Prolong drug circulation half-life
Bypass mechanisms of multidrug resistance
Excellent biocompatibility and biodegradability
Carry multiple drugs to achieve synergistic therapeutic effects
Reduce non-specific tissue uptake through passive (EPR effect) and active targeting (targeting agent modification)
Enhance drug solubility and stability
Revolutionary loading method for efficient encapsulation of poorly water-soluble (lipophilic) compound within the liposome aqueous core.
High encapsulation efficiency
Robust compound retention and product stability
This drug loading method significantly increases the functional-substance-to-lipid mass ratio to levels above those attained by conventional encapsulation techniques for poorly-water soluble compounds, and dramatically expands the range of drug compounds suitable to encapsulation within liposomes.
Efficient loading for water-soluble (hydrophilic) compounds within the aqueous core of the liposome.
High encapsulation efficiency with controlled drug release profile
Encapsulation of therapeutic compounds within the liposome’s hydrophobic lipid bilayer.
Selective for certain poorly-water soluble (hydrophobic) compound
Compounds with distinct physicochemical properties (e.g., both hydrophilic and lipophilic) can be efficiently co-encapsulated within the same liposome using combined techniques.
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